Neuroprotective effect of genistein in peripheral nerve injury

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Neuroprotective Effect of Genistein in Peripheral Nerve Injury.

AIM To investigate the effects of genistein in a rat model of sciatic nerve crush injury and complete sciatic nerve transection. The effects of genistein were compared with those of gabapentin, which is widely used in clinical practice for peripheral nerve injury. MATERIAL AND METHODS Forty-eight rats were randomly divided into six groups (8 rats in each group): group 1 (sham); group 2, sciat...

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The Effect of Ultrasound on Acceleration of Peripheral Nerve Injury

Background: Many people suffer from nerve injury. The time consuming nature of the treatments makes the condition worse. Therefore, finding a way to accelerate the process of nerve repair is very important.Objective: To determine the effect of ultrasound on the acceleration of crushed peripheral nerve regeneration.Methods: The experimental model included crushed rat’s sciatic nerve. 40 rats w...

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the effect of ultrasound on acceleration of peripheral nerve injury

background: many people suffer from nerve injury. the time consuming nature of the treatments makes the condition worse. therefore, finding a way to accelerate the process of nerve repair is very important. objective: to determine the effect of ultrasound on the acceleration of crushed peripheral nerve regeneration. methods: the experimental model included crushed rat’s sciatic nerve. 40 rats w...

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Neuroprotective Activity of Thioctic Acid in Central Nervous System Lesions Consequent to Peripheral Nerve Injury

Peripheral neuropathies are heterogeneous disorders presenting often with hyperalgesia and allodynia. This study has assessed if chronic constriction injury (CCI) of sciatic nerve is accompanied by increased oxidative stress and central nervous system (CNS) changes and if these changes are sensitive to treatment with thioctic acid. Thioctic acid is a naturally occurring antioxidant existing in ...

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Pathophysiology of Peripheral Nerve Injury

Peripheral nervous system (PNS) is a complex construction, which serves dual purpose. Firstly, it disseminates information from the central nervous systems and ensures that this information is interpreted to the target end organs. Secondly, it collects information from the periphery, translates it to nerve signals, processes it and feeds it back to the central nervous system. The PNS consists o...

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ژورنال

عنوان ژورنال: Turkish Neurosurgery

سال: 2016

ISSN: 1019-5149

DOI: 10.5137/1019-5149.jtn.18549-16.1